HBOC Cancer Risks

BRCA mutations are responsible for the majority of hereditary breast and ovarian cancer.4,5,6 Patients with a mutation in either the BRCA1 or BRCA2 gene have risks of up to 87% for breast cancer and up to 44% for ovarian cancer by age 70.4,6,7,8,9 Mutation carriers previously diagnosed with cancer also have a significantly increased risk of developing a second primary (new) cancer.8,10,11Genetic testing identifies patients who have germline mutations in the BRCA1 and BRCA2 genes.  This information is useful when developing risk-reducing strategies for these patients.