Prolaris ScoreTM

How can I tell how aggressive my cancer is?

Gleason score, stage, PSA and other factors can tell you how advanced your cancer is.  DRE and PSA tests alert you to the fact that you may have prostate cancer, but now there is a test that can help tell you how aggressive your cancer is. The Prolaris test from Myriad Genetic Laboratories gives your doctor a critical piece of additional information: a Prolaris Score which measures the aggressiveness of your tumor.

Prolaris was developed to help doctors predict prostate cancer aggressiveness, together with other clinical variables, such as: Gleason score and PSA. Technically, Prolaris measures how fast your tumor is growing.

The signature has been evaluated in four clinical studies:

  • A study of 366 patients which predicted biochemical recurrence in patients who had undergone radical prostatectomy
  • A study of 413 patients which predicted biochemical recurrence in patients who had undergone radical prostatectomy
  • A study of 337 patients which predicted ten year mortality risk in patients with clinically localized prostate cancer diagnosed by transurethral resection and managed conservatively (watchful waiting)
  • A study of 352 patients which predicted ten year mortality risk in patients with clinically localized prostate cancer diagnosed by needle biopsy and managed conservatively (watchful waiting)

Prolaris was a statistically significant predictor of clinical outcomes in all four studies. Prolaris provides unique additional information about your prognosis and may be used with other clinical factors to help your doctor recommend the treatment that you need.